Warning!

Warning: This blog is about primary infertility the second time around, so there might be mention of my DS.

Saturday, February 19, 2011

Breaking the Silence - Here's What's Been Happening

I know I've been silent on here ever since I announced that the first IVF for TTC#2 worked and I was pregnant. Here's the story on why.... It's long, so grab a beverage before you start reading.

Our retrieval was on Thanksgiving and the transfer 3 days later. We made the decision to put back 3 embryos, the same thing we did the past two IVFs. This decision was based on the advice from our RE, our past history of putting back 3, and the fact that this cycle required more and more stim drugs meaning it was getting even harder for my body to produce eggs. This was our last chance. All was going well and I felt some slight tugging and pressure a few days after the transfer, exactly as I had felt with my DS. Maybe this might work.

I went in 8 days after the transfer and my HCG level was 94! A positive result is anything over 20. But we're not out of the woods yet, it has to approximately double every 48 hours. Sure enough, 48 hours later it was 346, the next one was 1373 at 12 days past transfer. For perspective, with my DS on 12 days past transfer my HCG was at 326. My mind went into overdrive, uh-oh, I think we have multiples. I checked out betabase.info and while my numbers fell into the range of a singleton and twins, I knew something was up. DH and I started to prepare ourselves for having twins. Three days later, my HCG shot up to 4378. We had an ultrasound that same Monday at 4.5 weeks, but it was too early to see anything. I went back on Friday and we saw 3 gestational sacs - yes, 3. All 3 embryos that we put back had implanted. I cried right there on the table.

What had happened? Over the past 3 IVFs we've put back 7 embryos and only had 1 baby. How could all 3 have implanted? What were we going to do with 3 babies? The nurses all assured me that it was really early and a lot can happen. Something like 40-50% of triplet pregnancies lose one by 11 weeks. I turned to my Resolve chat boards, poured my heart out, and received amazing support from the ladies on there. We have all been through so many ups and downs together, and these ladies were able to share their own personal experiences around this and talk me down a bit. I started checking out tripletconnection.org to read about families with triplets. How many medical problems were there at birth, how do families cope day to day, what types of developmental delays, etc.

We were thinking that the first ultrasound would show twins and we would be able to say we were pg with twins. But with triplets! How do you even say that? We knew we couldn't look at people and show genuine happiness, we were scared to death, overwhelmed with emotion, financial thoughts, our lives completely turning upside down. I would have to quit my job and stay home. So I took the cowards way out and just posted that we were pg on this blog for those of you that were following the IVF, then remained silence. We had nothing more that we wanted to share at that time. I called family to say that we were pg, but avoided questions of "how many" by saying it was too early to tell.

At 6 weeks, all 3 were growing on track and we could see heart flutters. With Christmas approaching and the RE office closed for a few days, I was given a prescription for nausea since I would have triple the hormones and could have triple the morning sickness. I never filled that prescription. Other than exhaustion, I've felt fine. At 6.5 weeks, they were all growing on track and while we still couldn't hear their heartbeats, we were able to measure them between 104-133 beats per minute (bpm). At that point, the doctor told me he was just going to look around a little bit and make sure we weren't missing another one that might have split. While my feet were in stirrups, my leg started to shake. Another one? Sigh of relief, nothing more was found other than my still massively swollen ovaries producing triple the hormones.

At 7.5 weeks, I went to the OB for my first visit. All 3 were growing on track with heartbeats in the 160-168 range. I asked if my OB could handle this pregnancy. He's delivered hundreds of twins, but only 4 triplets. I was referred to a Maternal Fetal Medicine (MFM) specialist in the Medical Center. My OB told me that he takes a conservative approach to multiples and would recommend bedrest at 19 weeks for triplets, and if we lost one, it would be 24-28 weeks for twins. It's not medically necessary or proven, but the thought is that by staying off your feet and taking pressure off the cervix, pre-term labor can hopefully be avoided. We were all for that plan. After my whole almost dying incident while giving birth to DS, we want to be cautious. But wow, that meant I didn't have a whole lot of time left.

Later that week I saw the RE again, everyone was growing. I started researching the leave of absence and short term disability programs at work. If I stopped working before the babies were born, I would use up all my FMLA and only have 8 weeks after the birth for STD from a c-section. That's not enough especially if they spend time in the NICU. Instead, I'm going to cut back my hours to 25-30/week while on bedrest and hope to reduce some stress. It will be a pay hit for a few months but I should keep all of my benefits, accrue vacation time, and keep my STD and FMLA time for when they are born. The next step about my job won't be decided until after they are born.

At 9 weeks, saw the RE and they were all growing. One nurse in particular has been so supportive during all of this. Talking me through my overstressed and overwhelmed tears, providing the name of a counselor, and just patiently answering all of my questions. At 9.5 weeks, I saw the MFM and we talked about risks. We also talked about my MTHFR (I don't absorb folic acid and can have blood clots). He said that staying on my normal 3 doses of folic acid with B vitamins a day is enough to counteract the MTHFR, and that I no longer need to take the Lovenox blood thinner injections. Woo hoo! That was definitely positive and I stopped that very day. I still will take baby aspirin the whole way through for my own peace of mind.

Another RE visit, but since I was already being seen by the OB and MFM, this was to be my last appointment. I do recall taking a last look back at the office while I walked out the door, thinking that I would never be back. Whatever happens with this pg, I am done. Even if we lose them all, I am just done, I can not go back and do this again. The amount of physical and emotional pain, and the volume of tears that have been shed while trying to build a family had definitely taken their toll. I knew that if we lost them all, we could potentially try naturally, but I would never be back and we would most likely stay a family of 3.

Over the next few weeks we saw the MFM a few times and baby C was was not doing as well. With my age, the fertility drugs, and seeing baby C, we decided to do CVS (chorionic villius sampling) testing on baby A and B to see if they would be ok. It is a painful procedure. We were supposed to have results in 48 hours, but because of baby A and B's placenta being close to each other, the doc wasn't able to get enough tissue for the fast test. In fact, he thought he might have to go in again to get more tissue. Mine was transabdominal and they essentially take a large needle, stab it through your skin, fat, muscle and uterus to get tissue from the placenta to test the DNA cells. It literally took my breath away. Luckily I've learned a lot of coping skills over the years for dealing with physical pain and I used them to get through it. The thought of it being done "again" to get more tissue was agonizing. We waited an hour to see if the lab had enough tissue, which they did.

We waited 2 weeks to get the results. During that time we didn't have anymore ultrasounds. Even with it looking like we were losing baby C, there was nothing that could be done. It was definitely a mixed feeling. We've known all along that we had no idea how to handle triplets, and losing one makes everything more manageable (not that twins and a toddler won't be challenging enough), but we'd seen baby C on the ultrasound a number of times, wiggling and moving. It's heartbreaking to think that we'll never meet our child. The doc told us to take a break from all the appointments and wait for the results. We finally got the tests back on baby A and B and they are both genetically normal (no Down's Syndrome, Cystic Fibrosis, etc) and at this point we're not at risk of losing them. They are also both males. While we were thrilled to hear that they are healthy, DH and I were both a little sad that we wouldn't be having a little girl. We've shed another round of tears over the last few days, losing baby C and wondering if that would have been our little girl. Baby C's picture will be added to our infertility album, which holds pictures of all of our past embryos that never made it.

Here's the last picture we have of the 3 of them together. Baby A is on the far right with hands on his head, baby B is in the middle, upside down with feet at the top. Baby C is on the left/bottom, already looking a little smaller than the others.

But now we are ready to move on! I'm 14w2d, starting the 2nd trimester and ready to be excited about our growing family. I want to enjoy this pregnancy, my last one, be amazed by the kicks in my belly and keep these babies inside as long as possible. We'll be re-using all of DSs bedding, clothes, etc, but just today went out and bought a 2nd set of boy bedding. We're having twin boys, exciting and scary all at the same time!

Sunday, December 19, 2010

A Caveat and Request

Since you've been reading this blog and following our family building journey, we've announced to you that we are pregnant. However, we are not ready to make a general announcement. It is way too early in the game and we haven't even seen a heart flutter or heard a heartbeat yet. So, please do not share this news with others, congratulate us on Facebook, or make it public in any other way. Thanks for your understanding.

Saturday, December 18, 2010

Confirmed - It's Positive!

It worked on the first try! We're a little shocked after the number of tries it took for DS, and wanted to make sure it was really true. We had an ultrasound yesterday to confirm it. I'm officially 5w2d. I haven't actually calculated the due date yet but it will be in mid August, just 3 weeks after DSs due date.

Personally, I knew it was positive the day after bedrest. Call it intuition or whatever, but I just knew it, I had the same tugging and pulling sensation as last time. My HCG levels were high on Monday 12/6 and more than doubled by Wednesday 12/8. An ultrasound this week showed that my ovaries are still quite enlarged and there is fluid in my abdomen which was causing the pain I had all last week, although it has mostly subsided now.

I've started weaning off the steroids this past week and have one week left. I haven't slept past 4 am in 4 weeks and today got up at 3 am. I'm really hoping that it's the steroids causing the insomnia and that once I finally get off of them I'll be able to sleep again.

We're not out of the woods yet. Everyone knows that you normally don't tell people until 12 weeks because there is always a chance of miscarriage. We're still walking on eggshells a bit to make sure that everything works out. I'll continue all of my medications (except steroids) and will have weekly ultrasounds to check growth and make sure things are progressing.

In the meantime, we're excited to have a merry Christmas and get ready for our expanding family!

Thursday, December 9, 2010

Needles and Bruises

Have I ever mentioned how much I hate shots? At least for stims, I use an empty syringe to draw up the mixed medication and the needle is super sharp and slides in like butter. Ganirelix (to prevent me from ovulating) was a pre-filled syringe and that is probably the worst needle. You get to your skin and the needle just stops and you have to literally jab it through. Lovenox (daily blood thinner) isn't quite as bad as Ganirelix but it also has a pretty dull needle that has to really be jabbed into the skin, which of course causes more pain than a sharp needle. Why do pre-filled syringes have such dull needles? I seriously have no idea.

Then we get to the bruising. Last time I was pg and did the blood thinner injections the full 39 wks and my belly was all black, blue, purple and green. This time a nurse told me that I can prevent bruising by not applying any pressure after the injection. I was so excited! I've been doing that every time. I have gauze to wipe up the blood but I don't apply any pressure. Yeah, doesn't work. The left side is lovely shades of blue, green and yellow showing healing and fresh bruises. The right side has some yellow healing bruises along with some bright purple ones. Considering it's a relatively small area of real estate that the injections can go into (about 2 inches on either side of the belly button), the space available becomes even more limited due to the bruising.

But alas, I'm just venting. I know the injections are necessary and I just hope that it's a positive outcome. I'll continue to grin and bear it...with a little side venting every now and then :)

Monday, December 6, 2010

When Will I Know?

That's the question some people are asking, so here's the answer. It's not quite as simple as a fertile person who pees on a stick and announces they are pg. The trigger shot that I did almost 2 weeks ago contains the hormone HCG that makes your body ovulate in 36 hours. The artificial HCG hormone slowly leaves your body over about 10 days and as of Friday it was down to 6.

Now I want my HCG levels to go up, and almost double every 48 hours. My official Beta (pg test) uses serum (blood) HCG levels to determine pg and is technically this next Sunday which is 14dp3dt (14 days past 3 day transfer). I'll get my HCG levels M/W/F this week when I go in for blood tests, so I'll know which way it's trending. I'm hoping for an HCG of > 200 on Sunday to show a strong Beta.

If it's positive, I keep going in for bloodwork twice a week to make sure the HCG is still doubling and that my estrogen and progesterone levels are in range, otherwise my medication needs to be adjusted. I would have an ultrasound to confirm how many embryos implanted. Then ultrasounds once a week to hear the heartbeat, then to make sure there is a fetal pole and a yolk sac. Around 8 weeks I would go to the OB for my first ultrasound there, and then I would officially graduate from the REs office around 10-12 weeks. Embryos through IVF have been through a lot with all of the synthetic FSH and LH that was used to create the egg, so it's a little more cautious to make sure the pg will stick.

If it's negative and HCG levels are low, I start weaning off steroids and stop the other hormones, blood thinners, etc., but still have to go back in for bloodwork to make sure the HCG goes back to zero.

So this is the week where the late afternoon phone calls from the doctor have my heart pumping as I wait to hear if we'll have a Merry Christmas or a melancholy one. I know of at least 4 pg friends and more that are trying. Whatever the outcome, please understand that I won't share it right away. If it's positive, there are still a number of steps that I need to get through to feel confident that it's a viable pg. If it's negative, I'm going to need some time to grieve and get the tears under control before I can face swollen bellies and baby talk again.

Friday, December 3, 2010

My Maybe Babies

When I first started this blog I added some comments from an infertility album I started a few years ago to grieve, say goodbye, and hold the pictures of the embryos that my DH and I created that didn't make it. We get pictures of these embryos on transfer day and we talk to them, look at them and start to love our possible future babies.

Here are the 3 "maybe babies" that are inside me right now. We love you and hope that at least one of you snuggle in, implant and fully develop over the next 9 months.

8 cell embryo with tiny fragmentation, the little bubbles near the top. The nurse said this one looks like a pretty flower and is probably a girl :)
8 cell graded as grainy
6 cell graded as grainy
Ultrasound during the transfer. The little white spot on the upper right with the arrow under it is where the embryos were placed in my uterus. You could actually see the tiny 3 dots swoosh out of the catheter.

Tuesday, November 30, 2010

Final Day of Bedrest

I realize that no one really cares what I do on bedrest, but I'm bored, so I'm going to talk about it anyway. Yesterday my DH worked from home and was able to fill my water, bring me lunch, etc. in between meetings. During the day I read the 300 page book "Breakfast at Tiffany's", I watched "Eat, Pray, Love" and I did a meditation which led into a 3 hour nap. Mixed in there was writing on this blog, sending a few emails and just staring into space.

Today my DH had to go into the office. He prepped a cooler for me with some snacks and drinks, and put a plate of food in the fridge ready for me to pop in the microwave. I've got "Charlie St. Cloud" loaded in the DVD player and a few other movies recorded on the DVR, along with a few magazines within arms reach.

The bedrest pains have set in. My lower back, sides and shoulders ache from lying on them for 42 hours so far. But as predicted, the hardest part is not being able to interact with my DS. Sure he comes running over every once in a while to give me a high five, and I did get him to sit on the couch with me while we read a book on Sunday, but he's just not really the kind of kid that sits still to snuggle. He's off and going. I'm very much looking forward to tomorrow where I can finally give him a proper snuggle hug.

Tonight I'll start to prop myself up with some pillows and let my body start adjusting again. From past experience, I've about passed out my first day off bedrest because my blood pressure gets so low. I've got a doc appt at 9 am tomorrow to check my blood and see how my estrogen and progesterone are doing, then a full day of work.

As for my little embryos, nothing to report there. I'm hoping they are getting all comfy and burrowing in, but it'll be a while before I know anything. There are all sorts of symptoms, or lack of, that you can read into during the 2WW, but I'm attempting to not obsess on it all and just see what happens.